The link between cannabis use and psychotic-like experiences is largely the result of genetic factors

first_imgStudies have found an association between cannabis use and transient psychotic symptoms, such as unusual thoughts, suspiciousness, and hallucinatory experiences. A new study suggests that this relationship is mostly attributable to genetic predisposition.But the research, which appears in JAMA Psychiatry, found that person-specific factors also influence the association between psychotic-like experiences and cannabis use to a lesser extent.“I initially became interested in this topic as a result of trying to understand factors associated with the development of psychotic-like experiences (i.e., sub-clinical odd beliefs or perceptual distortions),” said study author Nicole R. Karcher of the Washington University School of Medicine in St Louis. “It is very important to understand who is at risk for the development of psychotic-like experiences, what role marijuana use plays in the development of psychotic-like experiences, and to what extent this relationship is the result of genetics versus environmental factors.”The researchers analyzed data from the Human Connectome Project and the Australian Twin Registry Cohort 3. The data allowed them to compare 4,674 individuals, including 758 pairs of monozygotic twins, 780 pairs of dizygotic twins, and 195 same-sex sibling pairs with no more than 2 years’ age difference.Karcher and her colleagues found that cannabis use was positively associated with psychotic-like experiences, even after controlling for a number of demographic variables and other substance use measures. But genetic factors accounted for 69.2% to 84.1% of the association.“The study indicates that the relationship between psychotic-like experiences and marijuana use is largely the result of shared genetics,” she explained to PsyPost.“However, there is a person-specific environmental component. This person-specific component was due to siblings who smoked more marijuana reporting greater psychotic-like experiences compared to siblings who reported smoking less marijuana. Overall, the results suggest that cannabis use prevention may be an important tool in preventing worsening of PLEs in individuals at increased genetic liability to PLEs and cannabis use,” Karcher continued.The study — like all research — contains some limitations. The data was cross-sectional, meaning the researchers could not determine the direction of causality.“Limitations of the study include that we could not directly address the issue of whether smoking more marijuana causes greater psychotic-like experiences (or whether it is actually the reverse — psychotic-like experiences lead to greater marijuana use),” Karcher explained.“Also, future research should examine the relationship between psychotic-like experiences and different varieties and components of marijuana, including whether synthetic marijuana is associated with psychotic-like experiences versus whether cannabidiol (CBD) is associated with evidence of reduced risk for psychotic-like experiences.”The study, “Genetic Predisposition vs Individual-Specific Processes in the Association Between Psychotic-like Experiences and Cannabis Use“, was authored by Nicole R. Karcher, Deanna M. Barch, Catherine H. Demers, David A. A. Baranger, Andrew C. Heath, Michael T. Lynskey, and Arpana Agrawal. LinkedIn Pinterest Share on Facebookcenter_img Share on Twitter Email Sharelast_img read more

admin

‘Plug & play’ energy storage system set for launch

first_imgSubscribe Get instant access to must-read content today!To access hundreds of features, subscribe today! At a time when the world is forced to go digital more than ever before just to stay connected, discover the in-depth content our subscribers receive every month by subscribing to gasworld.Don’t just stay connected, stay at the forefront – join gasworld and become a subscriber to access all of our must-read content online from just $270.last_img

admin

Don’t look now

first_imgStay at the forefront of thought leadership with news and analysis from award-winning journalists. Enjoy company features, CEO interviews, architectural reviews, technical project know-how and the latest innovations.Limited access to building.co.ukBreaking industry news as it happensBreaking, daily and weekly e-newsletters Get your free guest access  SIGN UP TODAY To continue enjoying Building.co.uk, sign up for free guest accessExisting subscriber? LOGIN Subscribe now for unlimited access Subscribe to Building today and you will benefit from:Unlimited access to all stories including expert analysis and comment from industry leadersOur league tables, cost models and economics dataOur online archive of over 10,000 articlesBuilding magazine digital editionsBuilding magazine print editionsPrinted/digital supplementsSubscribe now for unlimited access.View our subscription options and join our communitylast_img read more

admin

Clean sweep for Windies women

first_imgMercurial right-hander bats-woman Deandra Dottin belted an astonishing century as the West Indies (Windies) cricket team trounced Sri Lanka Women by 31 runs to sweep the three-match Twenty20 International series in Antigua Sunday night.Playing at Coolidge Cricket Ground, the 26-year-old Dottin carved out 112 off 67 deliveries as the hosts chalked up 159 for six off their 20 overs, after choosing to bat first.Dottin, of Barbados, smashed nine fours and five sixes on the way to becoming the first women player to score two T20 hundreds in a career, following her maiden one seven years ago during the T20 World Cup in the Caribbean.The Barbadian’s hundred was also her second of the year, coming on the heels of her unbeaten 104 against Pakistan in the Women’s 50-overs World Cup in England last July.Dottin, who was voted Player-of-the-Match, got support from Hayley Matthews who chipped in with 34 runs from 40 balls at the top of the order.In their reply, the Sri Lanka Women were held to 128 for five off their 20 overs despite half-centuries from wicketkeeper Rebeca Vandort (50) and Shahikala Siriwardene (50).Matthews returned later with her off-spin to claim four wickets for 18 runs from her four overs.The win ensured the Windies swept the entire series after their 3-0 whitewash in the ICC Women’s Championship ODIs in Trinidad a fortnight ago.For update on Windies women in T50 tournament, visit link: West Indies women beat Sri Lankalast_img read more

admin

Take a Friday night hayride in Farmington Hills

first_imgExperience fall colors and the changing season during Friday night Heritage Park hayrides, held through November 2.Rides leave every half hour from 5:30 p.m. to 7 p.m. (last ride). Afterward, roast marshmallows and sip cider around a cozy campfire, and explore the Nature Center, which is open until 7 p.m. on hayride nights.Pre-registration is strongly recommended, as only a limited number of spots will be available. Stay late after your hayride on Friday, October 26 for a Full Moon Friday Night Hike from 8 p.m. to 9 p.m.To register, visit https://recreg.fhgov.com. To learn more, call 248-477-1135 or write to asmith@fhgov.com. The Farmington Hills Nature Center is located in Heritage Park at 24915 Farmington Road. Reported by admin Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Pinterest (Opens in new window)last_img read more

admin

Dune Hugger: Beach User Fees

first_imgSpecial to the PRESSBeach User Fees or as some would rather call it, paid parking is coming to Gulf Boulevard next year by the way things look with the City of South Padre Island and the Texas General Land Office. So what does that mean? It means that, if all goes well for the City, visitors and residents will have to start paying to use the public beach parking spots on Padre Boulevard in order to access the city beaches. Up to $13 a day with an option to purchase a $50 “Annual Pass” would be the pricing for parking there. This is legal under the Texas Natural Resources Code 61 or the Open Beaches Act. That is not an issue. The spin on this by its supporters are that it will help make Gulf Boulevard safer for both residents and visitors by lowering the traffic on the road and add revenue to our very important Beach Maintenance Fund to help with adding parking options such as parking lots, cleaning the beach and add amenities for the beach users to utilize, such as bathrooms.I have been involved in this issue as the Surfrider Foundation South Texas Representative for 10 years and this plan specifically for the past four years. The way it is being sold is that it will cost the City of South Padre Island hardly anything as it will all be handled by a mobile application available to smart phones and the revenue will go into the aforementioned benefits to the beach. However, there are some serious issues that still remain that make me and others skeptical about the success of this program.The first issue is the system of payment itself. This would be done by a smartphone app that would allow the visitor to pay for their time in that spot effortlessly and those that do not own a phone capable of supporting that app can go to City Hall and purchase their pass manually. So let’s say that you have to go purchase the pass through City Hall. That means you actually have to go off of Gulf Boulevard and not even know if there would be a spot available when you went back.The second issue is enforcement. A vehicle will only show up on the system if someone has actually bought their time in a spot either through the app or physically at an outlet. Vehicles that have not bought their time will be invisible. The way the City has promoted the enforcement of this is by one individual on an ATV with an iPad scanning license plates for those that have tried to game the system. The other issue with enforcement is with the time period. A person could actually occupy the spot for up to 24 hours. Is this same individual supposed to chalk tires and then report back to the next shift whose responsibility it would be to ticket and tow the offending vehicle? Without this important aspect of enforcement it is very likely that condo complexes will take over these public parking spots to alleviate their problem of not planning enough parking for their own renters. Is there anyone out there that actually believes one person can actually handle this during the months of March, June, July and August? It is completely impossible! It is apparent that there will have to be more than just one individual involved in this process like the police. The problem with this is not only added expenses to the City’s General Fund but the fact that our police don’t even know how the restricted parking on the side feeder streets work. I actually was ticketed for parking in an authorized area a few weeks ago and that is five years after the restrictions have been in effect!Finally, safety. That is, after all, what this is for, right? The City must provide free parking in order to offset the paid parking according to the OBA and the GLO. A few spots on Gulf Boulevard such as the cul-de-sacs at Wanna Wanna, Boomerang Billy’s and Harbor will be provided but the majority are across Padre Boulevard (State Highway 100) and would require the visitor to either try and wait for only one Wave Bus that services the entire route or cross their family across the very busy main thoroughfare for SPI! So much for safety!In addition, the City already has recognized that this Beach User Fee program will not create any real revenue, if any, by seeking a bond proposal to finish the Gulf Boulevard improvements that must be done. This program will also not, in my opinion, alleviate traffic on Gulf or increase safety for our visitors while actually costing the City more than the program will be bringing in and not help fund amenities for our tourists.The proposed ordinance has been submitted to the Texas Register and public comments are open until August 31. If you would like to submit your comments, please submit them to Walter Talley at the General Land Office at walter.talley@glo.texas.gov. Want the whole story? Pick up a copy of the Port Isabel-South Padre Press, or subscribe to our E-Edition by clicking here. RelatedCouncil holds hearing to discuss parking issuesBY CHRISTINA R. GARZA Staff Writer press@portisabelsouthpadre.com The South Padre Island City Council on Wednesday held a public hearing to discuss comprehensive parking solutions. Staff Attorney Scottie Aplin of the Texas General Land Office (GLO) presented an overview of the Texas Open Beaches Act. The act requires local governments to…July 12, 2013In “News”Island parking talks heat upBy AARIN HARTWELL Special to the PRESS Parking issues on the Island dominated the City Council meeting last Wednesday, March 15, at City Hall on South Padre Island. Discussion of the city’s convention center renovation and expansion and proposed seasonal parking permit brought many spectators to the audience of the…May 23, 2013In “News”Taskforce mulls parking feesBy ABBEY KUNKLE Special to the PRESS February 12, 2015 Monday afternoon, Coastal Resource and Parks Administrator Reuben Treviño and City Manager Bill DiLibero attended the Shoreline Task Force meeting to update the committee on projects and improvements along the beach. Treviño came to the Task Force with a follow-up…February 13, 2015In “News”center_img Sharelast_img read more

admin

Menteri Luhut Belum Mau Ungkap Identitas Investor Untuk Proyek LRT Jakarta

first_imgDilansir KabarPenumpang.com dari laman globalindonesianvoices.com (29/8/2017), Menteri Koordinator Kelautan, Luhut binsar Pandjaitan belum mau membuka identitas dari calon investor yang akan mendanai proyek LRT tersebut. Luhut bersama jajarannya pun mengaku tengah melakuan pengawasan terhadap beberapa kementerian, salah satunya adalah Kementerian Perhubungan.Lebih lanjut, Luhut hanya memberikan bocoran mengenai kesediaan calon investor tersebut untuk mendanai proyek yang bernilai Rp 2 triliun tersebut. Pada awalnya, proyek ini akan didanai oleh negara. Diinfokan, pada laporan keuangan sebelumnya, jumlah dana yang harus dikeluarkan untuk menyelesaikan proyek LRT ini adalah senilai Rp 27 triliun dan uang tersebut akan masuk ke PT KAI sebagai investor proyek.Dilansir dari sumber terpisah, Rp 27 triliun tersebut terbagi dari dua sumber, yaitu Rp 9 triliun merupakan dana negara, sedangkan Rp 18 triliun sisanya merupakan pinjaman dari bank pemerintah, seperti Bank Mandiri, Bank BNI, dan Bank BRI, serta satu perusahaan pembiayaan infrastruktur, Sarana Multi Infrastruktur.Baca Juga: Sebagai Kota Termacet di Dunia, DKI Jakarta Raih Posisi Ketiga!Seperti yang diketahui sebelumnya, Pemerintah Pusat dan Pemkot DKI tengah bahu membahu dalam menghadirkan salah satu moda transportasi yang diharapkan mampu menjadi solusi kemacetan di Jakarta, yaitu MRT yang dijalankan oleh PT MRTJ. Dalam pembangunan fase I MRT Jakarta yang akan menghubungkan Lebak Bulus – Bundaran HI, Direktur Utama PT MRTJ, William P. Sabandar mengaku membutuhkan dana ekstra guna menyelesaikan proyek tersebut. PT MRTJ mengajukan form kekurangan dana kepada Pemerintah sebesar Rp 2,56 triliun. Dengan begitu, total dana yang dikeluarkan untuk menyelesaikan fase I ini mencapai Rp 16 triliun.Dengan dana super fantastis tersebut, maka tidak heran jika banyak elemen masyarakat yang mengharapkan kehadiran moda-moda transportasi baru ini dapat menjadi solusi kemacetan di Jakarta yang semakin hari semakin “memerah” ini. Pada tahun 2016 kemarin, Jakarta dinobatkan sebagai kota termacet ketiga di Dunia oleh sala satu pengembang aplikasi asal Negeri Kincir Angin, TomTom. Sungguh prestasi yang tidak membanggakan.Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)Like this:Like Loading… Related Pembangunan Jalur LRT Dalam mewujudkan proyek Light Rail Transit (LRT), salah satu investor yang berbasis di Singapura menunjukkan minatnya untuk mendanai proyek yang akan disandingkan dengan moda transportasi berbasis massal lainnya, seperti TransJakarta, Commuter Line Jabodetabek (KRL Jabodetabek), dan Mass Rapid Transit (MRT) yang hingga kini masih dalam proses pembangunan. Pemerintah sebenarnya mengharapkan campur tangan dari investor lokal yang juga turut serta dalam pengadaan LRT ini, yaitu PT. Adhi Karya.Baca Juga: Di Jakarta Segera Beroperasi MRT dan LRT, Tahukah Artinya?Diketahui, perkembangan pembangunan proyek LRT Jakarta ini sudah mencapai 15 persen. Bisa dikatakan, proyek ini akan mirip dengan KRL Jabodetabek, yang menghubungkan daerah sub-urban, seperti Bogor, Depok, dan Bekasi dengan titik-titik penting di pusat kota. Bedanya, dalam jaringan LRT ini, Tangerang tidak akan dilalui oleh LRT.last_img read more

admin

West Florida Ranked in Collegiate Baseball Preseason Poll

first_imgCOLLEGIATE BASEBALL POLL2016 SCHEDULE December 23, 2015 TUCSON, Ariz. – The University of West Florida baseball team ranks No. 39 in Collegiate Baseball’s NCAA Division II 2016 Preseason Poll. West Florida is coming off a 30-18 performance in 2015 and appeared in last year’s preseason poll at No. 35. UWF has five opponents on its 2016 schedule ranked in the poll, headlined by Tampa who earned the No. 1 overall ranking after being crowned NCAA Division II National Champions in 2015. West Florida will host Tampa during the second weekend of the season, as the Argos and Spartans will square off for a three-game series on Feb. 12-14. Gulf South Conference foes West Alabama, West Georgia and Alabama Huntsville earned rankings of No. 8, No. 27 and No. 30, respectively. Lee received votes to round out GSC appearances. UWF will also face No. 15-ranked North Georgia in a midweek series on April 12-13 for a nonconference two-game set in Pensacola. West Florida returns seven of nine players to the starting lineup for 2016, in addition to returning all three starting pitchers. Key returners include NCBWA South Region Pitcher of the Year Brandon Nagem and All-GSC selections Chase Kiefer, Alex Greene and Jarrod Petree. Florida Southern, UWF’s opening weekend opponent, also received votes in the poll. West Florida opens up its 2016 campaign on Feb. 6, on the road against the Mocs.   For information on all UWF athletics, visit www.GoArgos.com. #ARGOS# Print Friendly Versionlast_img read more

admin

Lantaran Bisa Bawa Sial, Sejumlah Maskapai Hilangkan Sejumlah Nomor Bangku

first_imgSumber: qantas.com Bagi Anda yang sering bepergian dengan menggunakan pesawat, pernahkah Anda iseng memperhatikan baris tempat duduk yang tersedia di dalam kabin? Teruntuk maskapai asing, biasanya ada deret angka yang tidak runut yang diberlakukan oleh pihak maskapai, atau ada juga maskapai yang menghilangkan nomor-nomor tertentu karena beranggapan bahwa angka-angka tersebut sebagai angka sial. Nah, siapa dari Anda yang sudah tahu mengenai hal ini? Atau bahkan baru tahu setelah membaca artikel ini? Yuk kita simak maskapai mana saja yang memberlakukan penomoran unik pada setiap armada yang dioperasikannya.Baca Juga: Jadi Baiknya Sebagai Penumpang Pesawat Duduk di Kursi Mana?Sebagaimana yang dilansir KabarPenumpang.com dari laman news.com.au (4/7/2019), sejumlah maskapai di luar sana seperti Singapore Airlines, Cathay Pacific, Qatar Airways, Emirates, dan United Airlines menolak untuk menggunakan nomor bangku 13 di dalam kabin mereka dan lebih memilih untuk menghapus nomor tersebut – pada maskapai ini menganggap bahwa 13 sebagai angka sial.Ilustrasi penomoran dari Boeing 777-300 milik Qatar Airways. Sumber: news.com.au Ketika kebanyakan maskapai memulai penomoran bangku dimulai dengan angka 1, tapi ada juga maskapai yang tidak memulai penghitungan nomor bangku dari angka 1. Sebut saja Boeing747-400 yang dioperasikan oleh AirChina, dimana maskapai ini menomori bangku di baris paling depan di dalam kabinnya dengan angka 11 hingga nomor 14 yang menandakan bahwa itu adalah kelas bisnis. Setelah 14, AirChina akan mulai menomori bangku mereka dengan angka 1, 2, 3 yang merupakan bangku first class, dan menggunakan nomor 31 ke atas untuk menandai bangku kelas ekonomi. Hhmmm, cukup rumit ya penomoran dari AirChina!Ilustrasi penomoran dari maskapai AirChina. Sumber: news.com.auMengingat ada angka 13 yang dianggap ‘keramat’ oleh sebagian maskapai, namun ada juga maskapai lain yang tetap menggunakan angka ini dan tidak menghiraukan soal stigma buruk tentang angka sial ini. Sebagian maskapai yang berasal dari daerah Asia malah enggan menggunakan angka 4 karena menurut kepercayaan mereka, 4 merupakan angka yang dipercaya dapat membawa kesialan.Sebagai contoh, salah satu maskapai yang tidak menggunakan angka 4 pada bangku penumpang di armada mereka adalah Cathay Pacific. Sementara diluar Asia, ada juga Lufthansa yang tidak menggunakan angka 13 dan 17 pada bangku penumpang di armada mereka yang dilatarbelakangi oleh hal yang sama selayaknya maskapai-maskapai yang sudah disebutkan tadi – membawa sial.Baca Juga: Dilema Seat Pitch, Maskapai Tambah Untung Penumpang MeranaTapi tenang saja, kendati penomoran pada bangku-bangku pesawat yang sudah disebutkan di atas ada yang tidak runut atau melompati nomor-nomor tertentu, Anda akan tetap bisa duduk di bangku yang tertera pada tiket Anda dengan cara menunjukkan boarding pass kepada awak kabin ketika proses boarding, dan mereka akan dengan senang hati menunjukkan dimana tempat duduk Anda.Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)Like this:Like Loading… RelatedYuk, Cari Tahu Makna Tersembunyi di Balik Nomor Penerbangan18/04/2018In “Domestik”Apa yang Harus Anda Lakukan Jika Didepak dari Penerbangan Akibat Overbooked?04/10/2019In “Bandara”Ini Dia Daftar Maskapai yang Belum Hentikan Penggunaan Boeing 737 MAX 814/03/2019In “Domestik”last_img read more

admin

Violence Mars Italian Football As Rival Serie A Fans Clash

first_imgSupporters of Serie A club Lecce were attacked by hundreds of rival fans from Bari as they travelled to Rome for Sunday’s top-flight clash against Roma, local media reported.The clashes occurred near Ofanto, between Bari and Foggia, in Italy’s southern Puglia region.Fans of Serie B side Bari covered the road with nails, forcing a bus carrying Lecce supporters to stop, with several injuries and the bus set on fire, the Quotidiano Di Puglia reported.Bari issued a statement condemning the attack, and offering their support to their local rivals in the heel of Italy.“These are incidents that have nothing to do with the values Bari have always supported and promoted,” the club wrote.Lecce returned to the top flight this season after back-to-back promotions and are three points above the relegation zone.Bari were relegated to Serie D following bankruptcy in 2018, and are currently in Serie C.RelatedWhy Astori And Not Masiello’ – Bari Fans Unveil Controversial BannerMarch 5, 2018In “Europe”Parma Handed Five-Point Deduction As Calaio Gets Two-Year BanJuly 23, 2018In “Europe”Inter Milan fan dies in hospital after clash with Napoli fansDecember 27, 2018In “Italy”last_img read more

admin